Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906766 | 0.78 | MAOA (0.36) | TSHRHSD17B10HPGDMAPK1CYP3A4 | |
| SCHEMBL11205516 | 0.72 | TSHR (0.38) | TSHRALDH1A1ALOX15ALOX12 | |
| SCHEMBL11208269 | 0.70 | MEN1 (0.39) | TSHRHSD17B10HPGDALDH1A1MAPT | |
| SCHEMBL8930738 | 0.67 | TSHR (0.59) | TSHRALDH1A1CYP1A2ALOX15ALOX12 | |
| SCHEMBL9218811 | 0.67 | CA1 (0.33) | TSHR | |
| SCHEMBL11210964 | 0.67 | CA1 (0.38) | TSHRHSD17B10HPGDCYP3A4RECQL | |
| SCHEMBL13871692 | 0.63 | SIRT1 (0.55) | CYP3A4ALDH1A1CYP1A2MAPTMEN1 | |
| SCHEMBL11038432 | 0.61 | HSD17B10 (0.52) | TSHRHSD17B10HPGDMAPK1CYP3A4 | |
| SCHEMBL8168896 | 0.60 | HSD17B10 (0.40) | TSHRHSD17B10HPGDMAPK1CYP3A4 | |
| SCHEMBL68191 | 0.60 | HSD17B10 (0.77) | TSHRHSD17B10HPGDMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095454-A2 | Nuclens-substituted pyrogallol derivatives | Gerot-Pharmazeutika Gesellschaft m.b.H. (AT) | 1983-11-30 | — | — | EP | disclosed |