Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | USP1 | O94782 | 1/20 | 0.33 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11202404 | 0.89 | PDCD1 (0.41) | CD274PDCD1KMT2AALDH1A1DPP4 | |
| SCHEMBL11209771 | 0.88 | CD274 (0.41) | CD274PDCD1KMT2ASCN8AHTR7 | |
| SCHEMBL11203834 | 0.88 | MEN1 (0.33) | KMT2AALDH1A1HTTPTGS2 | |
| SCHEMBL11204881 | 0.84 | ESR1 (0.38) | CD274PDCD1ALDH1A1KDM4ECTSA | |
| SCHEMBL11203836 | 0.84 | CD274 (0.37) | CD274PDCD1KMT2ADPP4MME | |
| SCHEMBL11205794 | 0.81 | KMT2A (0.43) | CD274PDCD1KMT2ADPP4MME | |
| SCHEMBL11206356 | 0.76 | CYP2D6 (0.33) | KMT2AALDH1A1LMNAL3MBTL1PPARG | |
| SCHEMBL6547626 | 0.76 | ADRA2A (0.42) | KMT2AHTR7ALDH1A1HTTPTGS2 | |
| SCHEMBL11208750 | 0.76 | PDCD1 (0.38) | CD274PDCD1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL10360593 | 0.76 | PDCD1 (0.46) | CD274PDCD1KMT2AALDH1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |