SCHEMBL11206398

SCHEMBL11206398

Cc1nc2cc3nc[nH]c3cc2nc1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.50
KDM4E B2RXH2 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALDH1A1 P00352 1/20 0.50
APEX1 P27695 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
MMP12 P39900 1/20 0.43
PRKCI P41743 1/20 0.42
BRD4 O60885 1/20 0.41
CREBBP Q92793 1/20 0.41
RAD52 P43351 1/20 0.41
CHRNB2 P17787 2/20 0.40
CHRNA4 P43681 2/20 0.40
CYP3A4 P08684 1/20 0.38
NAMPT P43490 1/20 0.38
XDH P47989 1/20 0.38
PKM P14618 1/20 0.38
QPCT Q16769 3/20 0.37
QPCTL Q9NXS2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14511179 0.82 MAPT (0.68) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL12445185 0.79 MAPT (0.65) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL14426850 0.79 MAPT (0.46) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL14419042 0.79 MAPT (0.46) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL15010385 0.78 KDM4E (0.48) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL30798772 0.78 KDM4E (0.48) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL12438615 0.76 POLB (0.50) MAPTKDM4ETDP1ALDH1A1APEX1
Dimedazol SCHEMBL312977 0.76 MAPT (0.56) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL2136974 0.76 MAPT (0.56) MAPTKDM4ETDP1ALDH1A1APEX1
SCHEMBL31268592 0.75 MAPT (0.50) MAPTKDM4ETDP1ALDH1A1APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP claimed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US claimed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP claimed
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP disclosed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US disclosed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP disclosed