Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15010385 | 1.00 | KDM4E (0.48) | KDM4EMAPTALDH1A1APEX1RECQL | |
| Phenazine SCHEMBL28566498 | 0.81 | KDM4E (0.50) | KDM4EMAPTALDH1A1TDP1NQO2 | |
| SCHEMBL14511179 | 0.80 | MAPT (0.68) | KDM4EMAPTALDH1A1APEX1RECQL | |
| SCHEMBL4132133 | 0.79 | KDM4E (0.52) | KDM4EMAPTALDH1A1APEX1RECQL | |
| SCHEMBL12445185 | 0.78 | MAPT (0.65) | KDM4EMAPTALDH1A1APEX1RECQL | |
| Bromide SCHEMBL23726605 | 0.78 | KDM4E (0.50) | KDM4EMAPTALDH1A1APEX1RECQL | |
| SCHEMBL11206398 | 0.78 | MAPT (0.50) | KDM4EMAPTALDH1A1APEX1RECQL | |
| SCHEMBL7229359 | 0.77 | NPC1 (0.58) | MAPTALDH1A1SMN1; SMN2RAB9ANPC1 | |
| Benzimidazole SCHEMBL18704815 | 0.76 | KDM4E (0.48) | KDM4EMAPTALDH1A1APEX1RECQL | |
| SCHEMBL4612924 | 0.75 | MAPT (0.79) | KDM4EMAPTALDH1A1TDP1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |