Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11365927 | 0.95 | KMT2A (0.46) | KMT2AGLAALOX5SMN1; SMN2MEN1 | |
| SCHEMBL11203799 | 0.89 | LMNA (0.43) | KMT2ASMN1; SMN2MEN1POLBLMNA | |
| SCHEMBL11208706 | 0.87 | MAPT (0.48) | KMT2AMEN1LMNAABCB11MAPT | |
| SCHEMBL11206652 | 0.87 | THRA (0.36) | KMT2AMEN1POLBLMNAABCB11 | |
| SCHEMBL7359104 | 0.87 | MAPT (0.48) | KMT2AMEN1LMNAABCB11MAPT | |
| SCHEMBL11201942 | 0.87 | THRA (0.36) | KMT2AMEN1POLBLMNAABCB11 | |
| SCHEMBL11201202 | 0.87 | KCNA3 (0.41) | KMT2AALOX5MEN1POLBLMNA | |
| SCHEMBL11206024 | 0.87 | KCNA3 (0.41) | KMT2AALOX5MEN1POLBLMNA | |
| SCHEMBL11203299 | 0.87 | KCNA3 (0.41) | KMT2AALOX5MEN1POLBLMNA | |
| SCHEMBL11208527 | 0.87 | KCNA3 (0.41) | KMT2AALOX5MEN1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |