Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.35 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL260743 | 0.83 | NLRP3 (0.36) | ALDH1A1TSHR | |
| SCHEMBL259449 | 0.83 | NLRP3 (0.36) | ALDH1A1TSHR | |
| SCHEMBL27921332 | 0.83 | ALDH1A1 (0.40) | CHRM5CHRM1CHRM3PGRCHRM2 | |
| SCHEMBL11638619 | 0.74 | MIF (0.30) | — | |
| SCHEMBL1871684 | 0.72 | ALDH1A1 (0.57) | ALDH1A1TSHR | |
| SCHEMBL10179480 | 0.71 | ALDH1A1 (0.51) | CHRM5CHRM1CHRM3PGRCHRM2 | |
| SCHEMBL28274095 | 0.71 | — | — | |
| SCHEMBL11637903 | 0.71 | — | — | |
| SCHEMBL1352910 | 0.71 | — | — | |
| SCHEMBL11640528 | 0.71 | LMNA (0.34) | ALDH1A1USP2ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014853-B1 | ANTHRACYCLINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Zaidanhojin Biseibutsu Kagaku Kenkyukai (JP) | 1983-06-01 | — | — | EP | disclosed |
| US-4303785-A | ETHERS OF ADRIAMYCIN AND DAUNORUBICIN | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1981-12-01 | — | — | US | disclosed |
| EP-0014853-A1 | Anthracycline derivatives, a process for their preparation and pharmaceutical compositions containing them | Zaidanhojin Biseibutsu Kagaku Kenkyukai (JP) | 1980-09-03 | — | — | EP | disclosed |