Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215599 | 0.83 | ALDH1A1 (0.53) | ALDH1A1POLBSMN1; SMN2KDM4EHPGD | |
| SCHEMBL11207032 | 0.80 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1POLBSMN1; SMN2KDM4E | |
| SCHEMBL9706011 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4EHTR1ALMNA | |
| SCHEMBL17322703 | 0.78 | ALDH1A1 (0.68) | ALDH1A1TDP1HTR1ANPC1RAB9A | |
| SCHEMBL11211145 | 0.75 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1KDM4EHPGDHSD17B10 | |
| SCHEMBL11211176 | 0.75 | ALDH1A1 (0.49) | ALDH1A1POLBHTR1A | |
| SCHEMBL24361267 | 0.74 | ALDH1A1 (0.56) | ALDH1A1POLBSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL5495355 | 0.74 | ALDH1A1 (0.68) | ALDH1A1POLBNPC1RAB9ALMNA | |
| SCHEMBL6836903 | 0.74 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2KDM4EHPGDCASP1 | |
| SCHEMBL11218149 | 0.73 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4EHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095454-A2 | Nuclens-substituted pyrogallol derivatives | Gerot-Pharmazeutika Gesellschaft m.b.H. (AT) | 1983-11-30 | — | — | EP | disclosed |