Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6836903 | 0.77 | ALDH1A1 (0.58) | ALDH1A1HTR1AKDM4ESMN1; SMN2ALOX15 | |
| SCHEMBL11211594 | 0.75 | ADRB2 (0.55) | ALDH1A1HTR1ASMN1; SMN2MAPK1 | |
| SCHEMBL11211176 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HTR1A | |
| SCHEMBL11211145 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HTR1AKDM4EHTTMAPK1 | |
| SCHEMBL11210025 | 0.74 | MAPT (0.54) | ALDH1A1HTR1AKDM4EALOX15 | |
| SCHEMBL9704953 | 0.73 | HTR1A (0.54) | ALDH1A1HTR1A | |
| SCHEMBL11207230 | 0.73 | ALDH1A1 (0.58) | ALDH1A1HTR1AKDM4ESMN1; SMN2 | |
| SCHEMBL10595250 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HTR1ASMN1; SMN2PKM | |
| SCHEMBL11207153 | 0.72 | ABCB1 (0.48) | ALDH1A1HTR1AKDM4EHTTSMN1; SMN2 | |
| SCHEMBL6298086 | 0.70 | NR2E1 (0.46) | ALDH1A1HTR1AKDM4ESMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095454-A2 | Nuclens-substituted pyrogallol derivatives | Gerot-Pharmazeutika Gesellschaft m.b.H. (AT) | 1983-11-30 | — | — | EP | disclosed |