SCHEMBL11207349

SCHEMBL11207349

CCc1ccccc1C(=O)ONC(=O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.62
KMT2A Q03164 2/20 0.62
POLB P06746 1/20 0.62
MAPT P10636 1/20 0.62
MIF P14174 1/20 0.50
KCNK3 O14649 1/20 0.46
KCNK9 Q9NPC2 1/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CLCN2 P51788 1/20 0.44
HTT P42858 2/20 0.43
HPGD P15428 1/20 0.43
MEN1 O00255 1/20 0.43
SLC16A3 O15427 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27798143 1.00 ALDH1A1 (0.62) ALDH1A1KMT2APOLBMAPTMIF
SCHEMBL27644924 0.88 LMNA (0.52) ALDH1A1KMT2APOLBMAPTMIF
SCHEMBL11149741 0.87 ALDH1A1 (0.54) ALDH1A1KMT2APOLBMAPTMIF
SCHEMBL27351517 0.83 HPGD (0.53) ALDH1A1KMT2APOLBMAPTNPC1
SCHEMBL11207843 0.82 ALDH1A1 (0.49) ALDH1A1KMT2ANPC1RAB9AL3MBTL1
SCHEMBL27900511 0.82 ALDH1A1 (0.49) ALDH1A1KMT2ANPC1RAB9AL3MBTL1
SCHEMBL28748022 0.81 ALDH1A1 (0.66) ALDH1A1KMT2APOLBMAPTMIF
SCHEMBL5724688 0.80 ALDH1A1 (0.46) ALDH1A1KMT2AMAPTL3MBTL1CLCN2
SCHEMBL28260858 0.79 ALDH1A1 (0.68) ALDH1A1KMT2APOLBMAPTMIF
SCHEMBL11528403 0.78 ALDH1A1 (0.47) ALDH1A1POLBMAPTL3MBTL1CLCN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0035291-B1 PROCESS FOR CARRYING OUT RADICAL REACTIONS AND SHAPED ARTICLES OF THE REACTION PRODUCT AKZO N.V. (NL) 1983-05-11 EP disclosed
US-4347342-A Process for initiating radical reactions employing hydroximic acid derivatives AKZONA INCORPORATED (US) 1982-08-31 US disclosed