SCHEMBL27900511

SCHEMBL27900511

CCc1ccccc1C(=O)ONC(C)=O

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
LMNA P02545 2/20 0.49
CLCN2 P51788 1/20 0.44
TSHR P16473 2/20 0.43
HTT P42858 2/20 0.41
F2R P25116 1/20 0.41
KDM4E B2RXH2 1/20 0.41
HSD17B10 Q99714 2/20 0.41
CFTR P13569 1/20 0.41
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
UTS2R Q9UKP6 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KMT2A Q03164 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11207843 1.00 ALDH1A1 (0.49) ALDH1A1LMNACLCN2TSHRHTT
Piperidine SCHEMBL27966029 0.87 SLC6A2 (0.40) ALDH1A1LMNACLCN2TSHRHTT
SCHEMBL11149242 0.86 ALDH1A1 (0.50) ALDH1A1LMNATSHRHTTKDM4E
SCHEMBL28121355 0.85 ALDH1A1 (0.48) ALDH1A1LMNATSHRKDM4EHSD17B10
SCHEMBL5724688 0.84 ALDH1A1 (0.46) ALDH1A1LMNACLCN2TSHRHTT
SCHEMBL11528403 0.82 ALDH1A1 (0.47) ALDH1A1LMNACLCN2TSHRHTT
SCHEMBL6406685 0.82 ALDH1A1 (0.42) ALDH1A1LMNACLCN2TSHRHTT
SCHEMBL27798143 0.82 ALDH1A1 (0.62) ALDH1A1CLCN2HTTKDM4EL3MBTL1
SCHEMBL28229486 0.82 F2R (0.55) ALDH1A1LMNACLCN2HTTF2R
SCHEMBL11207349 0.82 ALDH1A1 (0.62) ALDH1A1CLCN2HTTKDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104606128-B A kind of fast dissolving pharmaceutical composition 辉凌公司 2018-02-23 CN disclosed
CN-104797240-A Composition for immediate and extended release FERRING BV 2015-07-22 CN disclosed
CN-104606128-A A FAST DISSOLVING PHARMACEUTICAL COMPOSITION FERRING BV 2015-05-13 CN disclosed
CN-102834091-B Fast dissolving pharmaceutical composition FERRING BV 2015-04-22 CN disclosed
CN-102834091-A Fast dissolving pharmaceutical composition FERRING BV 2012-12-19 CN disclosed
CN-102821755-A Fast dissolving pharmaceutical composition FERRING BV 2012-12-12 CN disclosed