Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 6/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854444 | 0.64 | LMNA (0.51) | GAKABCB1 | |
| SCHEMBL18520396 | 0.64 | ALDH1A1 (0.41) | NOS1IDO1 | |
| SCHEMBL19984155 | 0.63 | PDE10A (0.38) | IDO1 | |
| SCHEMBL1586433 | 0.63 | ALDH1A1 (0.47) | — | |
| SCHEMBL8399554 | 0.63 | ESR1 (0.48) | — | |
| SCHEMBL11200180 | 0.61 | ABCB1 (0.42) | CDC7DBF4GAKABCB1 | |
| SCHEMBL25246795 | 0.60 | — | — | |
| SCHEMBL5128161 | 0.60 | LMNA (0.37) | ABCB1 | |
| SCHEMBL11319827 | 0.59 | MAPK1 (0.39) | GAKABCB1 | |
| SCHEMBL18791148 | 0.59 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082023-A2 | Thienopyrimidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1983-06-22 | — | — | EP | disclosed |