⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17926550 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL30189809 | 0.68 | LMNA (0.33) | — | |
| SCHEMBL19783530 | 0.68 | LMNA (0.33) | — | |
| SCHEMBL4597901 | 0.66 | LMNA (0.42) | — | |
| SCHEMBL16541497 | 0.65 | PI4KA (0.34) | — | |
| SCHEMBL1193873 | 0.64 | ADORA3 (0.33) | — | |
| SCHEMBL22865268 | 0.62 | — | — | |
| SCHEMBL18791148 | 0.61 | KDM4E (0.36) | — | |
| SCHEMBL4068928 | 0.61 | LMNA (0.37) | — | |
| SCHEMBL29350081 | 0.61 | LMNA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116262758-B | 7-Methylthiazolo [5,4-d ] pyrimidine compound, preparation method and application thereof | 上海博悦生物科技有限公司 | 2025-02-28 | — | — | CN | disclosed |
| WO-2023109158-A1 | 7-METHYLTHIAZOLO[5,4-D]PYRIMIDINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海博悦生物科技有限公司 | 2023-06-22 | — | — | WO | disclosed |
| WO-2023109158-A1 | 7-METHYLTHIAZOLO[5,4-D]PYRIMIDINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海博悦生物科技有限公司 | 2023-06-22 | — | — | WO | disclosed |
| CN-116262758-A | 7-methylthiazolo [5,4-d ] pyrimidine compound, preparation method and application thereof | 上海博悦生物科技有限公司 | 2023-06-16 | — | — | CN | disclosed |