Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.67 |
| ▸ | NPC1 | O15118 | 7/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970256 | 0.88 | KDM4E (0.58) | DYRK1ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL18494063 | 0.84 | DYRK1A (0.67) | DYRK1ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL10935232 | 0.79 | DYRK1A (0.76) | DYRK1ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL3113684 | 0.79 | RAB9A (0.61) | DYRK1ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL28247185 | 0.79 | DYRK1A (0.60) | DYRK1ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL30563626 | 0.79 | RAB9A (0.61) | DYRK1ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL30017067 | 0.79 | DYRK1A (0.60) | DYRK1ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL6068319 | 0.78 | DYRK1A (0.70) | DYRK1ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL2055271 | 0.78 | DYRK1A (0.58) | DYRK1ASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL6275004 | 0.78 | DYRK1A (0.58) | DYRK1ASMN1; SMN2NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043013-B1 | PROCESS FOR THE PREPARATION OF 2-CHLORO-BENZOTHIAZOLES | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-06-01 | — | — | EP | disclosed |
| EP-0043013-A1 | Process for the preparation of 2-chloro-benzothiazoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-06 | — | — | EP | disclosed |