Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 4/20 | 0.76 |
| ▸ | RAB9A | P51151 | 9/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.64 |
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.56 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ACP1 | P24666 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936043 | 0.86 | PIK3CA (0.77) | DYRK1ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL11303998 | 0.83 | NPC1 (0.80) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL10936133 | 0.83 | DYRK1A (0.74) | DYRK1ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL10936004 | 0.82 | DYRK1A (0.75) | DYRK1ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL5928965 | 0.82 | DYRK1A (0.75) | DYRK1ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL6068319 | 0.81 | DYRK1A (0.70) | DYRK1ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL10596177 | 0.81 | RAB9A (0.81) | RAB9ASMN1; SMN2NPC1KDM4EALDH1A1 | |
| SCHEMBL7786534 | 0.80 | CASP2 (0.77) | DYRK1ARAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL11207412 | 0.79 | DYRK1A (0.72) | DYRK1ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL10873161 | 0.79 | MAPT (0.61) | DYRK1ARAB9ASMN1; SMN2NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051560-B1 | MONOAZOPIGMENTS CONTAINING HETEROCYCLIC NUCLEI, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1985-01-16 | — | — | EP | disclosed |
| US-4400319-A | Monoazo pigments containing heterocycles, and high-molecular organic materials dyed therewith | CIBA-GEIGY CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| EP-0051560-A1 | Monoazopigments containing heterocyclic nuclei, their preparation and use | CIBA-GEIGY AG (CH) | 1982-05-12 | — | — | EP | disclosed |