Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208230 | 0.89 | MAPT (1.00) | ALDH1A1TDP1TP53MAPTCYP1A2 | |
| SCHEMBL9584276 | 0.85 | ALDH1A1 (0.74) | ALDH1A1TDP1TP53MAPTCYP1A2 | |
| SCHEMBL14584231 | 0.84 | ALDH1A1 (0.77) | ALDH1A1TDP1TP53MAPTCYP1A2 | |
| SCHEMBL11325997 | 0.83 | ALDH1A1 (0.71) | ALDH1A1TDP1TP53MAPTCYP1A2 | |
| SCHEMBL6752911 | 0.80 | ALDH1A1 (0.66) | ALDH1A1TDP1TP53MAPTCYP1A2 | |
| SCHEMBL8768499 | 0.78 | ALDH1A1 (0.63) | ALDH1A1TDP1TP53MAPTCYP1A2 | |
| Hippuric Acid SCHEMBL16798097 | 0.78 | ALDH1A1 (0.63) | ALDH1A1TDP1TP53MAPTCYP1A2 | |
| SCHEMBL28544728 | 0.77 | ALDH1A1 (0.62) | ALDH1A1TDP1TP53MAPTCYP1A2 | |
| SCHEMBL25285696 | 0.77 | MAPT (0.66) | ALDH1A1TDP1TP53MAPTCYP1A2 | |
| SCHEMBL1018418 | 0.76 | MAPT (0.66) | ALDH1A1TDP1TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017068-B1 | MIXTURES CONTAINING AZODICARBON AMIDE AND ALPHA-AMIDO SULFONES, THEIR PREPARATION AND USE AS A BLOWING AGENTS | BAYER AG (DE) | 1983-01-12 | — | — | EP | disclosed |
| US-4280004-A | ACTIVATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |
| EP-0017068-A1 | Mixtures containing azodicarbon amide and alpha-amido sulfones, their preparation and use as a blowing agents | BAYER AG (DE) | 1980-10-15 | — | — | EP | disclosed |