Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.79 |
| ▸ | TP53 | P04637 | 1/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.79 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207452 | 0.89 | ALDH1A1 (1.00) | MAPTALDH1A1TP53TDP1CYP1A2 | |
| SCHEMBL8957221 | 0.82 | MAPT (0.69) | MAPTALDH1A1TP53TDP1GAA | |
| SCHEMBL15791835 | 0.82 | MAPT (0.70) | MAPTALDH1A1TP53TDP1CYP1A2 | |
| SCHEMBL11306682 | 0.82 | MAPT (0.70) | MAPTALDH1A1TP53TDP1HSD11B1 | |
| SCHEMBL7129375 | 0.81 | MAPT (0.68) | MAPTALDH1A1TP53TDP1GAA | |
| SCHEMBL7927400 | 0.81 | MAPT (0.68) | MAPTALDH1A1TP53TDP1HSD11B1 | |
| SCHEMBL25285696 | 0.80 | MAPT (0.66) | MAPTALDH1A1TP53TDP1CYP1A2 | |
| SCHEMBL11084341 | 0.79 | MAPT (0.66) | MAPTALDH1A1TP53TDP1GAA | |
| SCHEMBL1018418 | 0.79 | MAPT (0.66) | MAPTALDH1A1TP53TDP1GAA | |
| SCHEMBL11313154 | 0.79 | MAPT (0.66) | MAPTALDH1A1TP53TDP1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
| EP-0017068-B1 | MIXTURES CONTAINING AZODICARBON AMIDE AND ALPHA-AMIDO SULFONES, THEIR PREPARATION AND USE AS A BLOWING AGENTS | BAYER AG (DE) | 1983-01-12 | — | — | EP | disclosed |
| US-4280004-A | ACTIVATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-07-21 | — | — | US | disclosed |
| EP-0017068-A1 | Mixtures containing azodicarbon amide and alpha-amido sulfones, their preparation and use as a blowing agents | BAYER AG (DE) | 1980-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | PRKCH, AIP, PRKCE | MAPT 3655/4885ALDH1A1 4689/4885TP53 4474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.