SCHEMBL1120746

SCHEMBL1120746

CC1=Cc2c(C(C)C)cc(C(C)C)cc2C1[Hf](C)(C)(=[SiH2])C1C(C)=Cc2c(C(C)C)cc(C(C)C)cc21

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
FABP3 P05413 2/20 0.31
FABP4 P15090 2/20 0.31
FABP5 Q01469 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL819245 0.98 GABRA1 (0.31) GABRA1GABRB2FABP3FABP4
Hydrochloric Acid SCHEMBL6438065 0.85 GABRA1 (0.32) GABRA1GABRB2FABP3FABP4FABP5
Hydrochloric Acid SCHEMBL8456038 0.84 FABP3 (0.33) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL1050750 0.82 GABRA1 (0.30) GABRA1GABRB2
Hydrochloric Acid SCHEMBL8457816 0.80
Hydrochloric Acid SCHEMBL8457800 0.80
Hydrochloric Acid SCHEMBL8460046 0.80
SCHEMBL17415228 0.80 GABRA1 (0.32) GABRA1GABRB2
Hydrochloric Acid SCHEMBL8607036 0.80
Hydrochloric Acid SCHEMBL818812 0.79 FAAH (0.32) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102282-B1 MULTIMODAL POLYETHYLENE COMPOSITION, MIXED CATALYST AND PROCESS FOR PREPARING THE COMPOSITION BASELL POLYOLEFINE GMBH (DE) 2011-02-09 EP disclosed