Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.32 |
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 known ✓ | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 known ✓ | P18507 | 1/20 | 0.32 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.32 |
| ▸ | GABRB3 known ✓ | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 known ✓ | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 known ✓ | P34903 | 1/20 | 0.32 |
| ▸ | HTR2B known ✓ | P41595 | 1/20 | 0.32 |
| ▸ | GABRA2 known ✓ | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 known ✓ | P48169 | 1/20 | 0.32 |
| ▸ | GABRA6 known ✓ | Q16445 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17415228 | 0.98 | GABRA1 (0.32) | FAAHCA1CA2LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL4474251 | 0.81 | MEN1 (0.30) | HTR2C | |
| Hydrochloric Acid SCHEMBL819245 | 0.81 | GABRA1 (0.31) | GABRA1GABRB2 | |
| SCHEMBL17386635 | 0.81 | FAAH (0.31) | FAAHCA1CA2LMNACYP1A2 | |
| SCHEMBL17415133 | 0.79 | SLC6A2 (0.30) | SLC6A2 | |
| SCHEMBL1120746 | 0.79 | GABRA1 (0.32) | GABRA1GABRB2 | |
| SCHEMBL20590577 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL16393753 | 0.77 | HTR2C (0.34) | HTR2C | |
| SCHEMBL17386979 | 0.77 | LMNA (0.33) | FAAHCA1CA2LMNACYP1A2 | |
| SCHEMBL818811 | 0.77 | LMNA (0.33) | FAAHCA1CA2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2760958-B1 | SYSTEMS, METHODS AND COMPOSITIONS FOR PRODUCTION OF TIE-LAYER ADHESIVES | EQUISTAR CHEM LP (US) | 2020-08-12 | — | — | EP | disclosed |
| EP-2673315-B1 | POLYETHYLENE FILMS | EQUISTAR CHEM LP (US) | 2019-03-20 | — | — | EP | disclosed |
| US-10005864-B2 | Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer | JAPAN POLYETHYLENE CORPORATION (JP) | 2018-06-26 | — | — | US | disclosed |
| EP-3078670-B1 | METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER | JAPAN POLYETHYLENE CORP (JP) | 2017-12-27 | — | — | EP | disclosed |
| US-20170320981-A1 | METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER | JAPAN POLYETHYLENE CORPORATION (JP) | 2017-11-09 | — | — | US | disclosed |
| US-9783625-B2 | Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer | JAPAN POLYETHYLENE CORPORATION (JP) | 2017-10-10 | — | — | US | disclosed |
| EP-1943281-B1 | HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE | BASELL POLYOLEFINE GMBH (DE) | 2017-09-20 | — | — | EP | disclosed |
| US-9676971-B2 | Systems, methods and compositions for production of tie-layer adhesives | EQUISTAR CHEMICALS, LP (US) | 2017-06-13 | — | — | US | disclosed |
| EP-2966096-B1 | METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER | JAPAN POLYETHYLENE CORP (JP) | 2017-04-26 | — | — | EP | disclosed |
| EP-2963045-B1 | METHOD FOR PRODUCING OLEFIN POLYMER WITH A METALLOCENE BASED CATALYST, AND OLEFIN POLYMER | JAPAN POLYETHYLENE CORP (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-1753794-B8 | POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION | BASELL POLYOLEFINE GMBH (DE) | 2008-07-16 | — | — | EP | disclosed |
| WO-2008077530-A2 | MULTIMODAL POLYETHYLENE COMPOSITION, MIXED CATALYST AND PROCESS FOR PREPARING THE COMPOSITION | BASELL POLYOLEFINE GMBH (DE) | 2008-07-03 | — | — | WO | disclosed |
| EP-1753794-B1 | POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION | BASELL POLYOLEFINE GMBH (DE) | 2008-06-04 | — | — | EP | disclosed |
| US-20070255033-A1 | Polyethylene for Injection Moldings | BASELL POYOLEFINE GMBH (DE) | 2007-11-01 | — | — | US | disclosed |
| US-20070213205-A1 | Polyethylene and Catalyst Composition for its Preparation | BASELL POLYOLEFINE GMBH (DE) | 2007-09-13 | — | — | US | disclosed |
| WO-2007042252-A1 | HYBRID CATALYST SYSTEMS SUPPORTED ON MAGNESIUM HALIDE | BASELL POLYOLEFINE GMBH (DE) | 2007-04-19 | — | — | WO | disclosed |
| EP-1753794-A1 | POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION | Basell Polyolefine GmbH (DE) | 2007-02-21 | — | — | EP | disclosed |
| EP-1740623-A1 | POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION | Basell Polyolefine GmbH (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005103100-A1 | POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION | BASELL POLYOLEFINE GMBH (DE) | 2005-11-03 | — | — | WO | disclosed |
| WO-2005103095-A1 | POLYETHYLENE AND CATALYST COMPOSITION FOR ITS PREPARATION | BASELL POLYOLEFINE GMBH (DE) | 2005-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320981-A1 | METALLOCENE COMPOUND, CATALYST FOR OLEFIN POLYMER, METHOD FOR PRODUCING OLEFIN POLYMER, AND OLEFIN POLYMER | CPNE4, PIN4, PIN1 | CA2 4498/4885GABRA1 4643/4885GABRB1 4824/4885 |
| US-10005864-B2 | Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer | CPNE4, PPOX, PIN1 | CA2 4618/4885GABRA1 4425/4885GABRB1 4724/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.