Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | THRA | P10827 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 4/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27968387 | 1.00 | ESR1 (0.34) | ESR1THRATHRBSMPD1S1PR2 | |
| SCHEMBL11118617 | 0.84 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL21051141 | 0.78 | SMN1; SMN2 (0.37) | TSHR | |
| SCHEMBL6002127 | 0.78 | TSHR (0.41) | ALDH1A1TP53TSHRLMNA | |
| SCHEMBL8351572 | 0.78 | TSHR (0.41) | ALDH1A1TP53TSHRLMNA | |
| SCHEMBL27338617 | 0.78 | TSHR (0.41) | ALDH1A1TP53TSHRLMNA | |
| SCHEMBL6003116 | 0.76 | LTA4H (0.41) | ALDH1A1TP53TSHRLMNA | |
| SCHEMBL27617373 | 0.75 | TP53 (0.46) | TP53TSHR | |
| Water SCHEMBL28779273 | 0.75 | PPARA (0.49) | S1PR3PLA2G2AALDH1A1TP53TSHR | |
| SCHEMBL27626904 | 0.75 | PPARA (0.49) | S1PR3PLA2G2AALDH1A1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027940-B1 | PROCESS FOR PREPARING URETHANES | BAYER AG (DE) | 1983-09-14 | — | — | EP | disclosed |
| EP-0027940-A1 | Process for preparing urethanes | BAYER AG (DE) | 1981-05-06 | — | — | EP | disclosed |