SCHEMBL11118617

SCHEMBL11118617

CCON(C=O)c1ccc(C)c(N(C=O)OCC)c1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ALDH3A1 P30838 1/20 0.30
ALDH1A3 P47895 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11207463 0.84 ESR1 (0.34) ALDH1A1
SCHEMBL27968387 0.84 ESR1 (0.34) ALDH1A1
SCHEMBL11100692 0.78 ALDH1A1 (0.33) ALDH1A1
SCHEMBL28253562 0.73 ESR1 (0.39) ALDH1A1MEN1KMT2AALDH3A1ALDH1A3
SCHEMBL28253465 0.73 ESR1 (0.39) ALDH1A1MEN1KMT2AALDH3A1ALDH1A3
SCHEMBL9628168 0.72 KDM4E (0.36) ALDH1A1MEN1KMT2A
SCHEMBL509868 0.72 ALDH1A1 (0.38) ALDH1A1MEN1KMT2A
SCHEMBL27347287 0.71 ALDH1A1 (0.32) ALDH1A1ALDH3A1ALDH1A3
SCHEMBL28472818 0.71 ALDH1A1 (0.50) ALDH1A1MEN1KMT2A
SCHEMBL27778437 0.71 ALOX15 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102348679-B Carbamate compound and method for producing same, and isocyanate and method for producing same MITSUI CHEMICALS INC 2014-09-10 CN disclosed
CN-103492364-A Method for manufacturing tolylene diisocyanate MITSU CHEMICALS INC 2014-01-01 CN disclosed
US-4430505-A UREA, PRIMARY AMINES, ALCOHOLS BAYER AKTIENGESELLSCHAFT (DE) 1984-02-07 US disclosed