SCHEMBL11207680

SCHEMBL11207680

CCC(CCOC)C(C)(C)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.32
CA1 P00915 1/20 0.32
ALDH1A1 P00352 1/20 0.31
MAPK1 P28482 1/20 0.31
PRSS1 P07477 1/20 0.30
CTSG P08311 1/20 0.30
CTRB1 P17538 1/20 0.30
CMA1 P23946 1/20 0.30
CYP2C9 P11712 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4106618 0.79 CHRM1 (0.41) CA2CA1ALDH1A1MAPK1PRSS1
SCHEMBL8689396 0.79 TSHR (0.38) CA2ALDH1A1MAPK1CYP2C9HSD17B10
SCHEMBL19565563 0.74 TSHR (0.31)
SCHEMBL8842792 0.74 CA2 (0.45) CA2MAPK1
SCHEMBL6856895 0.74 CA2 (0.36) CA2CA1MAPK1CYP2C9HSD17B10
SCHEMBL6945282 0.74 ACACB (0.44) CA2MAPK1CYP2C9HSD17B10
SCHEMBL22181478 0.73 GPR84 (0.47) CA2MAPK1
SCHEMBL28372293 0.73 ALDH1A1 (0.31) ALDH1A1
SCHEMBL9871824 0.72 CA2 (0.34) CA2MAPK1
Ammonia Solution, Strong SCHEMBL27914146 0.72 GPR84 (0.46) CA2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0080275-A1 Preparation of azoiminoether hydrochlorides from azonitriles and their hydrolysis to azocarboxylic esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-06-01 EP disclosed