SCHEMBL11207918

SCHEMBL11207918

Cc1cc(Br)c(OC(Br)C(C)Br)c(Br)c1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MCL1 Q07820 1/20 0.32
MAPT P10636 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11171954 0.85 HSD17B10 (0.36) CA2CA4
SCHEMBL12440967 0.71 MAPT (0.41) MEN1KMT2AMCL1MAPTL3MBTL1
SCHEMBL6577546 0.68 KDM4E (0.31) MEN1KMT2A
SCHEMBL16334835 0.68 LMNA (0.33) MEN1KMT2AMCL1MAPT
SCHEMBL13429928 0.68 LMNA (0.33) MEN1KMT2AMCL1
SCHEMBL3683983 0.67 CA2 (0.54) MEN1KMT2AMAPTL3MBTL1CA2
SCHEMBL3316427 0.66 LMNA (0.34) MEN1KMT2AMCL1
SCHEMBL12514195 0.66 MEN1 (0.37) MEN1KMT2AMCL1MAPTL3MBTL1
SCHEMBL3840761 0.65 HSD17B10 (0.34)
SCHEMBL9858387 0.65 HSD17B10 (0.37) MEN1KMT2ACA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0026310-B1 FIRE PROTECTION FINISH FOR RESOL-TYPE RESINOUS LAMINATES Chemische Fabrik Kalk GmbH (DE) 1983-07-27 EP disclosed