Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537774 | 0.91 | HSD17B10 (0.39) | HSD17B10ALOX12ALOX15LMNANPSR1 | |
| SCHEMBL10781184 | 0.83 | ALOX12 (0.39) | HSD17B10ALOX12ALOX15LMNANPSR1 | |
| SCHEMBL765589 | 0.81 | ALOX12 (0.47) | HSD17B10ALOX12ALOX15LMNANPSR1 | |
| SCHEMBL11171954 | 0.80 | HSD17B10 (0.36) | HSD17B10ALOX12ALOX15LMNANPSR1 | |
| SCHEMBL6280186 | 0.79 | ALOX12 (0.35) | HSD17B10ALOX12ALOX15LMNANPSR1 | |
| SCHEMBL6285002 | 0.77 | HSD17B10 (0.41) | HSD17B10ALOX12ALOX15LMNANPSR1 | |
| SCHEMBL10607884 | 0.73 | HSD17B10 (0.33) | HSD17B10ALOX12ALOX15LMNANPSR1 | |
| SCHEMBL11691799 | 0.72 | ALDH1A1 (0.41) | HSD17B10ALOX12ALOX15LMNANPSR1 | |
| SCHEMBL3840761 | 0.72 | HSD17B10 (0.34) | HSD17B10ALOX12ALOX15LMNANPSR1 | |
| SCHEMBL3413335 | 0.72 | HSD17B10 (0.38) | HSD17B10ALOX12ALOX15LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0192885-B1 | HALOGENATED BISPHENOL A ETHER FLAME RETARDANT FOR ABS POLYMERS | GREAT LAKES CHEMICAL CORPORATION (US) | 1991-03-13 | — | — | EP | disclosed |
| US-4567218-A | ACRYLONITRILE-BUTADIENE-STRYENE TERPOLYMER | GREAT LAKES CHEMICAL CORPORATION (US) | 1986-01-28 | — | — | US | disclosed |