SCHEMBL11208256

SCHEMBL11208256

CN(C)C(=O)Nc1ccc(Oc2ccccc2)c(Cl)c1

nearest known ligand 0.63

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PNLIP P16233 8/20 0.63
APEX1 P27695 1/20 0.61
PARG Q86W56 2/20 0.59
STK39 Q9UEW8 1/20 0.59
POLB P06746 1/20 0.56
ESRRA P11474 1/20 0.52
GCGR P47871 1/20 0.52
PARP1 P09874 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11446051 0.89 APEX1 (0.61) PNLIPAPEX1STK39ESRRAGCGR
SCHEMBL11163646 0.89 PNLIP (0.55) PNLIPAPEX1POLB
SCHEMBL6285132 0.86 ESRRA (0.69) PNLIPPARGSTK39POLBESRRA
SCHEMBL11584161 0.84 STK39 (0.64) PNLIPAPEX1STK39
SCHEMBL21295351 0.83 PNLIP (0.63) PNLIPPARGSTK39POLBESRRA
SCHEMBL11177802 0.83 APEX1 (0.58) PNLIPAPEX1PARGPOLBESRRA
SCHEMBL21295379 0.83 PNLIP (0.66) PNLIPPARGSTK39POLBGCGR
SCHEMBL1701888 0.83 XIAP (0.65) PNLIPAPEX1POLBESRRA
SCHEMBL63260 0.82 APEX1 (0.69) APEX1POLB
SCHEMBL8536442 0.82 APEX1 (0.69) APEX1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4399072-A HERBICIDE, FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-08-16 US disclosed
US-4280835-A Herbicidal N-phenyl-N-methylurea derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-07-28 US disclosed