Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL11207622 | 0.91 | SMN1; SMN2 (0.35) | CYP3A4CYP2C19SMN1; SMN2CYP19A1NPY5R | |
| SCHEMBL11208138 | 0.77 | LMNA (0.42) | CYP3A4KDM4ELMNAGAAL3MBTL1 | |
| Pyridine SCHEMBL11569632 | 0.77 | KDM4E (0.36) | CYP3A4KDM4EGAA | |
| Pyridine SCHEMBL11210901 | 0.75 | LMNA (0.32) | CYP3A4CYP2C19SMN1; SMN2LMNA | |
| SCHEMBL11212673 | 0.73 | LMNA (0.38) | CYP3A4KDM4ELMNAGAAL3MBTL1 | |
| Pyridine SCHEMBL11569873 | 0.73 | CYP17A1 (0.39) | CYP3A4CYP2C19SMN1; SMN2KDM4ELMNA | |
| Pyridine SCHEMBL11257784 | 0.73 | — | — | |
| Pyridine SCHEMBL11209411 | 0.72 | NPC1 (0.30) | SMN1; SMN2CYP19A1KDM4E | |
| Pyridine SCHEMBL11210777 | 0.72 | KMT2A (0.43) | CYP3A4CYP2C19SMN1; SMN2CYP19A1KDM4E | |
| Pyridine SCHEMBL11209087 | 0.72 | TSHR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003897-B1 | PHOSPHINEGOLD(I)SALTS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1983-05-25 | — | — | EP | disclosed |
| EP-0003897-A1 | Phosphinegold(I)salts, process for their preparation and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-09-05 | — | — | EP | disclosed |