Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208138 | 0.95 | LMNA (0.42) | LMNACYP2A6HDAC3HDAC1HDAC2 | |
| SCHEMBL6931661 | 0.82 | — | — | |
| SCHEMBL11208466 | 0.78 | CYP3A4 (0.39) | LMNAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL11604805 | 0.75 | LMNA (0.42) | LMNACYP2A6HDAC3HDAC1HDAC2 | |
| SCHEMBL9579813 | 0.73 | SMN1; SMN2 (0.40) | LMNACYP2A6HDAC3HDAC1HDAC2 | |
| SCHEMBL7557896 | 0.72 | ACHE (0.44) | LMNACYP2A6HTTGSK3BCES2 | |
| SCHEMBL2546807 | 0.71 | SMN1; SMN2 (0.43) | LMNAHDAC3HDAC1HDAC2ALDH1A1 | |
| SCHEMBL11312850 | 0.70 | ALDH1A1 (0.44) | LMNACYP2A6IDO1ALDH1A1L3MBTL1 | |
| SCHEMBL10764615 | 0.70 | ESR1 (0.48) | LMNAALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL11202847 | 0.70 | CYP2A6 (0.42) | CYP2A6HDAC3HDAC1HDAC2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003897-B1 | PHOSPHINEGOLD(I)SALTS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1983-05-25 | — | — | EP | disclosed |
| EP-0003897-A1 | Phosphinegold(I)salts, process for their preparation and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-09-05 | — | — | EP | disclosed |
| US-4096250-A | ANTI-ARTHRITIC | SMITHKLINE CORPORATION (US) | 1978-06-20 | — | — | US | disclosed |