Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537661 | 0.95 | HDAC8 (0.61) | ALDH1A1ACHEKMT2AHSD17B10HDAC8 | |
| SCHEMBL11754615 | 0.90 | ALDH1A1 (0.62) | ALDH1A1ACHEKMT2AHSD17B10HDAC8 | |
| SCHEMBL1436043 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ACHEKMT2AHSD17B10HDAC8 | |
| SCHEMBL30984444 | 0.83 | ALDH1A1 (0.60) | ALDH1A1ACHEKMT2AHSD17B10HDAC8 | |
| SCHEMBL29986677 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ACHEKMT2AHSD17B10HDAC8 | |
| SCHEMBL10672732 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ACHEKMT2AHSD17B10HDAC8 | |
| SCHEMBL30984472 | 0.83 | ALDH1A1 (0.56) | ALDH1A1ACHEKMT2AHSD17B10HDAC8 | |
| SCHEMBL7342447 | 0.82 | HDAC8 (0.57) | ALDH1A1ACHEKMT2AHSD17B10HDAC8 | |
| SCHEMBL877279 | 0.81 | KMT2A (0.73) | ALDH1A1ACHEKMT2AHSD17B10HDAC8 | |
| SCHEMBL5041554 | 0.81 | ALDH1A1 (0.60) | ALDH1A1ACHEKMT2AHSD17B10HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4399151-A | USING A-SUBSTITUTERD AMINES OR A-SUBSTITUTED AMINO ACIDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4134918-A | ENZYME INHIBITORS, ANTIBODY INHIBITORS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1979-01-16 | — | — | US | disclosed |