Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL11203406 | 0.96 | CYP2D6 (0.34) | CYP2D6CYP3A4CYP2C9CYP2C19CYP1A2 | |
| Pyridine SCHEMBL11213166 | 0.88 | KDM4E (0.32) | KDM4ENPC1 | |
| Pyridine SCHEMBL11205969 | 0.85 | KDM4E (0.33) | CYP3A4KDM4EKMT2ATDP1 | |
| SCHEMBL2938616 | 0.83 | LTA4H (0.47) | CYP2D6CYP3A4CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL11209432 | 0.78 | LTA4H (0.43) | CYP2D6CYP3A4CYP2C9CYP2C19CYP1A2 | |
| Pyridine SCHEMBL11206542 | 0.78 | ALDH1A1 (0.35) | TSHRL3MBTL1ALDH1A1MAPTPOLB | |
| Pyridine SCHEMBL11208438 | 0.77 | KDM4E (0.36) | CYP3A4TSHRKDM4ETDP1 | |
| Pyridine SCHEMBL11204444 | 0.77 | KDM4E (0.32) | KDM4E | |
| SCHEMBL2929963 | 0.76 | LTA4H (0.46) | CYP3A4LTA4HTSHRHTTSMN1; SMN2 | |
| SCHEMBL21403902 | 0.76 | LTA4H (0.46) | CYP3A4LTA4HTSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003897-B1 | PHOSPHINEGOLD(I)SALTS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1983-05-25 | — | — | EP | disclosed |