Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182911 | 0.91 | TP53 (0.39) | LMNATP53MEN1KMT2AMAPT | |
| SCHEMBL11206708 | 0.86 | CD274 (0.44) | LMNAMEN1KMT2APOLBMAPT | |
| SCHEMBL473259 | 0.82 | DPP4 (0.38) | TP53KMT2APOLBMAPTSMN1; SMN2 | |
| Water SCHEMBL474768 | 0.80 | DPP4 (0.37) | TP53KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL9184965 | 0.80 | ALDH1A1 (0.40) | LMNATP53MEN1KMT2APOLB | |
| SCHEMBL9185899 | 0.79 | TP53 (0.40) | TP53 | |
| SCHEMBL10601329 | 0.78 | IDH1 (0.41) | LMNATP53MEN1KMT2AMAPT | |
| SCHEMBL11202177 | 0.76 | POLB (0.37) | LMNATP53MEN1KMT2APOLB | |
| SCHEMBL27512807 | 0.76 | TP53 (0.48) | LMNATP53 | |
| SCHEMBL8679020 | 0.75 | CD274 (0.47) | KMT2APOLBPTGDR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |