Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11199823 | 0.82 | THRB (0.36) | POLBMEN1KMT2ASMN1; SMN2THRB | |
| SCHEMBL11201347 | 0.81 | PDCD1 (0.40) | POLBMEN1KMT2ASMN1; SMN2THRB | |
| SCHEMBL17697638 | 0.77 | PDCD1 (0.48) | POLBMEN1KMT2ASMN1; SMN2ESR2 | |
| SCHEMBL11208473 | 0.76 | LMNA (0.38) | POLBMEN1KMT2ASMN1; SMN2THRB | |
| SCHEMBL10601329 | 0.75 | IDH1 (0.41) | MEN1KMT2ASMN1; SMN2TP53ESR2 | |
| SCHEMBL11206708 | 0.74 | CD274 (0.44) | POLBMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL9066733 | 0.74 | IDH1 (0.49) | POLBSMN1; SMN2TP53LMNAALDH1A1 | |
| SCHEMBL31345536 | 0.74 | IDH1 (0.49) | POLBSMN1; SMN2TP53LMNAALDH1A1 | |
| SCHEMBL9184965 | 0.73 | ALDH1A1 (0.40) | POLBMEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL10759635 | 0.72 | KDM4E (0.39) | POLBMEN1KMT2ASMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |