Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208473 | 0.86 | LMNA (0.38) | FFAR1FFAR4LMNAALDH1A1HTT | |
| SCHEMBL11201347 | 0.82 | PDCD1 (0.40) | CD274PDCD1HTR7LMNAALDH1A1 | |
| SCHEMBL11197019 | 0.80 | HTR7 (0.49) | CD274PDCD1FOLH1FFAR1FFAR4 | |
| SCHEMBL473270 | 0.79 | PDCD1 (0.50) | CD274PDCD1FOLH1KMT2ADPP4 | |
| SCHEMBL11198848 | 0.78 | TP53 (0.41) | L3MBTL1 | |
| SCHEMBL9185898 | 0.78 | CSNK2A2 (0.41) | MAPK1 | |
| SCHEMBL27618792 | 0.78 | PDCD1 (0.48) | CD274PDCD1FOLH1KMT2ADPP4 | |
| Water SCHEMBL27696696 | 0.78 | PDCD1 (0.48) | CD274PDCD1FOLH1KMT2ADPP4 | |
| SCHEMBL11382363 | 0.78 | PDCD1 (0.48) | CD274PDCD1FOLH1KMT2ADPP4 | |
| SCHEMBL5562618 | 0.78 | SLC5A2 (0.47) | CD274PDCD1FOLH1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4371726-A | Composition suitable for mechanical power transmission and process for operating traction drives | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 1983-02-01 | — | — | US | disclosed |