Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | SHBG | P04278 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.53 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentagestrone SCHEMBL146311 | 0.88 | SHBG (0.53) | LMNASHBGCYP2C19MEN1NR3C1 | |
| Pentagestrone SCHEMBL21405771 | 0.86 | SHBG (0.51) | LMNASHBGCYP2C19MEN1NR3C1 | |
| SCHEMBL11517418 | 0.86 | SHBG (0.59) | LMNASHBGCYP2C19MEN1NR3C1 | |
| SCHEMBL11219426 | 0.85 | FNTA (0.49) | LMNASHBGCYP2C19MEN1NR3C1 | |
| SCHEMBL10901169 | 0.84 | SRD5A2 (0.41) | LMNASHBGCYP2C19MEN1NR3C1 | |
| SCHEMBL11339756 | 0.81 | TDP1 (0.46) | LMNAMEN1NR3C1KMT2AAR | |
| SCHEMBL11339761 | 0.81 | TDP1 (0.46) | LMNAMEN1NR3C1KMT2AAR | |
| SCHEMBL11505885 | 0.81 | SRD5A2 (0.41) | SHBGCYP2C19NR3C1ARPGR | |
| SCHEMBL11505888 | 0.81 | SRD5A2 (0.41) | SHBGCYP2C19NR3C1ARPGR | |
| SCHEMBL11505886 | 0.81 | SRD5A2 (0.41) | SHBGCYP2C19NR3C1ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093853-A1 | Substituted derivatives of 3-isopropyl cyclopentanone, their preparation and use as perfumes and compositions containing these derivatives | HÜLS AKTIENGESELLSCHAFT (DE) | 1983-11-16 | — | — | EP | disclosed |
| US-4329294-A | Process for preparing 17α-hydroxy-20-ketosteroids | EASTMAN KODAK COMPANY (US) | 1982-05-11 | — | — | US | disclosed |