Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.56 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.53 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208571 | 0.86 | LMNA (0.56) | SHBGLMNACYP2C19MEN1NR3C1 | |
| SCHEMBL9195965 | 0.83 | SHBG (0.53) | SHBGLMNACYP2C19MEN1NR3C1 | |
| SCHEMBL24358654 | 0.83 | SHBG (0.53) | SHBGLMNACYP2C19MEN1NR3C1 | |
| SCHEMBL24358655 | 0.83 | SHBG (0.53) | SHBGLMNACYP2C19MEN1NR3C1 | |
| Pentagestrone SCHEMBL146311 | 0.82 | SHBG (0.53) | SHBGLMNACYP2C19MEN1NR3C1 | |
| Pentagestrone SCHEMBL21405771 | 0.81 | SHBG (0.51) | SHBGLMNACYP2C19MEN1NR3C1 | |
| SCHEMBL11514918 | 0.81 | SHBG (0.60) | SHBGLMNACYP2C19MEN1NR3C1 | |
| SCHEMBL11519273 | 0.81 | ESR1 (0.47) | SHBGCYP2C19ARSRD5A2ESR1 | |
| SCHEMBL11519269 | 0.81 | ESR1 (0.47) | SHBGCYP2C19ARSRD5A2ESR1 | |
| SCHEMBL11509705 | 0.80 | TDP1 (0.46) | LMNANR3C1ARPGRSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150126-A | ANTITUMOR AND ANTICARCINOGENIC AGENTS AND ANIBODY INHIBITORS | AKTIEBOLAGET LEO (SE) | 1979-04-17 | — | — | US | disclosed |