Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420694 | 0.88 | CA2 (0.72) | CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL10709036 | 0.87 | CA2 (0.58) | CA2SMN1; SMN2ALDH1A1THRB | |
| SCHEMBL8520963 | 0.86 | CA2 (0.70) | CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL10414456 | 0.86 | CA2 (0.70) | CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL581719 | 0.86 | CASP3 (0.63) | GAASMN1; SMN2ALDH1A1CASP3SENP8 | |
| SCHEMBL10568997 | 0.86 | CASP3 (0.63) | GAASMN1; SMN2ALDH1A1CASP3SENP8 | |
| SCHEMBL10533113 | 0.84 | CASP3 (0.61) | GAASMN1; SMN2ALDH1A1CASP3SENP8 | |
| SCHEMBL10571533 | 0.84 | CASP3 (0.61) | GAASMN1; SMN2ALDH1A1CASP3SENP8 | |
| SCHEMBL3220040 | 0.84 | CASP3 (0.61) | GAASMN1; SMN2ALDH1A1CASP3SENP8 | |
| SCHEMBL3220290 | 0.84 | CASP3 (0.61) | GAASMN1; SMN2ALDH1A1CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081321-A1 | 2-Aminophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-06-15 | — | — | EP | disclosed |