Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 6/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6738820 | 0.78 | LMNA (0.56) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL118317 | 0.78 | LMNA (0.56) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL7529452 | 0.75 | LMNA (0.53) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL10748056 | 0.74 | ALDH1A1 (0.58) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL11059794 | 0.72 | ALDH1A1 (0.49) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| Dimethylcarbate SCHEMBL28139696 | 0.72 | LMNA (0.50) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL11725965 | 0.71 | ALDH1A1 (0.61) | ALDH1A1HSD17B10PGRGAAPTGS1 | |
| SCHEMBL13266254 | 0.70 | TDP1 (0.46) | ALDH1A1MAPK1HPGDMAOABRD4 | |
| SCHEMBL20483902 | 0.70 | DRD2 (0.48) | ALDH1A1HPGDMAOABRD4CREBBP | |
| SCHEMBL5543882 | 0.69 | BRD4 (0.45) | ALDH1A1KDM4EHPGDMAOABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012452-B1 | PHOSPHORIC ACID ESTERS AND THEIR USE IN PESTICIDAL COMPOSITIONS | BAYER AG (DE) | 1983-02-09 | — | — | EP | disclosed |
| EP-0000127-B1 | INSECTICIDAL AND ACARICIDAL COMPOSITIONS, THEIR MANUFACTURE AND THEIR USE | BAYER AG (DE) | 1982-10-20 | — | — | EP | disclosed |
| EP-0030661-A2 | Insecticidal and acaricidal agents containing propargyl esters of thiono-phosphoric acids | BAYER AG (DE) | 1981-06-24 | — | — | EP | disclosed |
| EP-0012452-A2 | Phosphoric acid esters and their use in pesticidal compositions | BAYER AG (DE) | 1980-06-25 | — | — | EP | disclosed |
| EP-0000127-A1 | Insecticidal and acaricidal compositions, their manufacture and their use | BAYER AG (DE) | 1979-01-10 | — | — | EP | disclosed |