Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24061321 | 0.83 | TSHR (0.61) | CYP3A4ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL7754593 | 0.82 | ALDH1A1 (0.65) | CYP3A4ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL17365323 | 0.80 | CYP3A4 (0.61) | CYP3A4ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL11297032 | 0.78 | KMT2A (0.49) | ALDH1A1RAB9AKDM4EHPGDPGR | |
| SCHEMBL20852437 | 0.77 | AR (0.62) | — | |
| SCHEMBL14241325 | 0.76 | TSHR (0.64) | CYP3A4ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL9645123 | 0.76 | CYP3A4 (0.56) | CYP3A4ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL10816910 | 0.76 | MEN1 (0.56) | ALDH1A1RAB9AHPGDTSHRPOLB | |
| SCHEMBL10815837 | 0.76 | KMT2A (0.56) | ALDH1A1RAB9AHPGDTSHRPOLB | |
| SCHEMBL14266363 | 0.75 | SAE1 (0.57) | ALDH1A1RAB9AKDM4EHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035734-B1 | 1-(ACYLAMINO-ARYLOXY-)2-HYDROXY-3-ALKINYL-AMINO PROPANES AND PROCESSES FOR THEIR MANUFACTURE | C.H. BOEHRINGER SOHN (DE) | 1983-09-21 | — | — | EP | disclosed |
| US-4344964-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS | C. H. BOEHRINGER SOHN (DE) | 1982-08-17 | — | — | US | disclosed |
| EP-0035734-A1 | 1-(Acylamino-aryloxy-)2-hydroxy-3-alkinyl-amino propanes and processes for their manufacture | C.H. BOEHRINGER SOHN (DE) | 1981-09-16 | — | — | EP | disclosed |