Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221906 | 0.87 | ALDH1A1 (0.55) | KMT2APGRALDH1A1KDM4EGLA | |
| SCHEMBL23709701 | 0.83 | KMT2A (0.48) | KMT2APGRALDH1A1KDM4EGLA | |
| SCHEMBL7754593 | 0.82 | ALDH1A1 (0.65) | KMT2AALDH1A1KDM4EGLACA12 | |
| SCHEMBL9313903 | 0.80 | KMT2A (0.57) | KMT2AALDH1A1KDM4EGLACA12 | |
| SCHEMBL11209050 | 0.78 | CYP3A4 (0.51) | KMT2APGRALDH1A1KDM4ECA12 | |
| SCHEMBL15678237 | 0.77 | KMT2A (0.54) | KMT2AALDH1A1KDM4EGLACA12 | |
| SCHEMBL20459116 | 0.77 | AR (0.60) | PGRALDH1A1GLASMN1; SMN2LMNA | |
| SCHEMBL13009075 | 0.76 | KMT2A (0.53) | KMT2AALDH1A1KDM4EGLACA12 | |
| SCHEMBL12309897 | 0.75 | PGR (0.56) | KMT2APGRALDH1A1KDM4ECA12 | |
| SCHEMBL13390684 | 0.74 | KDM4C (0.57) | KMT2AALDH1A1KDM4EGLACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344964-A | HYPOTENSIVE AGENTS, ANTIARRHYTHMIA AGENTS | C. H. BOEHRINGER SOHN (DE) | 1982-08-17 | — | — | US | disclosed |
| EP-0035734-A1 | 1-(Acylamino-aryloxy-)2-hydroxy-3-alkinyl-amino propanes and processes for their manufacture | C.H. BOEHRINGER SOHN (DE) | 1981-09-16 | — | — | EP | disclosed |