Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | CDC7 | O00311 | 3/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6528671 | 0.85 | PNMT (0.40) | IDO1CYP3A4AGXTPNMTHTR3E | |
| SCHEMBL11266744 | 0.84 | IDO1 (0.39) | IDO1TAAR1DAOPIN1MAOA | |
| SCHEMBL11208194 | 0.82 | MAOB (0.47) | MAOB | |
| SCHEMBL11208197 | 0.82 | MAOB (0.47) | MAOB | |
| SCHEMBL11202432 | 0.80 | IDO1 (0.43) | IDO1AGXTCDC7DBF4TAAR1 | |
| SCHEMBL11273357 | 0.78 | ACP1 (0.35) | ACP1TAAR1 | |
| SCHEMBL11205166 | 0.73 | AGXT (0.32) | IDO1AGXT | |
| SCHEMBL11225024 | 0.73 | KDM4E (0.32) | — | |
| SCHEMBL11215797 | 0.72 | — | — | |
| SCHEMBL10744133 | 0.72 | ACP1 (0.35) | ACP1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034474-B1 | SUBSTITUTED IMIDAZOLES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Farmos-Yhtyma Oy (FI) | 1983-01-26 | — | — | EP | disclosed |
| US-4333947-A | HYPOTENSIVE AGENTS, BACTERICIDES, FUNGICIDES | FARMOS-YHTYMA OY (FI) | 1982-06-08 | — | — | US | disclosed |
| EP-0034474-A1 | Substituted imidazoles, their preparation and pharmaceutical compositions containing the same | Farmos-Yhtyma Oy (FI) | 1981-08-26 | — | — | EP | disclosed |