SCHEMBL19027273

SCHEMBL19027273

CNC(=O)N(C1CC1)C1CC1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NQO1 P15559 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11209209 0.88 TSHR (0.50) TSHRALDH1A1
SCHEMBL31607256 0.80 SLC6A2 (0.41) TSHR
SCHEMBL967284 0.77
SCHEMBL965716 0.77 CCR5 (0.39) ALDH1A1L3MBTL1
SCHEMBL5827188 0.74 HSD11B1 (0.32)
SCHEMBL22006649 0.73 ALDH1A1 (0.38) TSHRALDH1A1L3MBTL1
SCHEMBL689399 0.72 TSHR (0.45) TSHRALDH1A1
SCHEMBL9547544 0.72 EPHX2 (0.41) TSHRALDH1A1
SCHEMBL19027646 0.72 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL969305 0.70 L3MBTL1 (0.41) TSHRALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10779540-B2 Benzamide compounds and their use as herbicides BASF SE (DE) 2020-09-22 US disclosed
EP-3390372-B1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2020-06-03 EP disclosed
US-20200157086-A1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2020-05-21 US disclosed
WO-2017102275-A1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES BASF SE (DE) 2017-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200157086-A1 BENZAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES CBR3, NR2C2, H1-2 TSHR 799/4885ALDH1A1 765/4885L3MBTL1 1679/4885
US-10779540-B2 Benzamide compounds and their use as herbicides DDT, DNPH1, BBOX1 TSHR 2289/4885ALDH1A1 74/4885L3MBTL1 2635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.