Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14673781 | 0.89 | USP2 (0.42) | USP2PLA2G2CHSD17B10THRBKDM4E | |
| SCHEMBL22613629 | 0.89 | USP2 (0.42) | USP2PLA2G2CHSD17B10THRBKDM4E | |
| Methacrylic Acid SCHEMBL11210689 | 0.78 | USP2 (0.53) | USP2PLA2G2CHSD17B10THRBKDM4E | |
| SCHEMBL5837613 | 0.75 | TSHR (0.39) | THRBKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL5672798 | 0.75 | ALDH1A1 (0.44) | THRBTSHRTDP1 | |
| SCHEMBL9614400 | 0.75 | USP2 (0.40) | USP2PLA2G2CTHRBKDM4EDUSP3 | |
| SCHEMBL14673855 | 0.75 | USP2 (0.41) | USP2PLA2G2CHSD17B10THRBKDM4E | |
| SCHEMBL5907719 | 0.73 | THRB (0.58) | USP2PLA2G2CHSD17B10THRBKDM4E | |
| SCHEMBL1398234 | 0.73 | TSHR (0.41) | THRBKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL5838352 | 0.73 | TSHR (0.41) | THRBKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410674-A | Silicone-vinyl acetate composition for contact lenses | IVANI EDWARD J | 1983-10-18 | — | — | US | disclosed |