SCHEMBL22613629

SCHEMBL22613629

C=C(C)C(=O)O[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C.CCCOCC(O)CO

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.42
PLA2G2C Q5R387 1/20 0.34
HSD17B10 Q99714 1/20 0.34
THRB P10828 1/20 0.33
KDM4E B2RXH2 1/20 0.33
DUSP3 P51452 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 3/20 0.33
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14673781 0.89 USP2 (0.42) USP2PLA2G2CHSD17B10THRBKDM4E
SCHEMBL11209288 0.89 USP2 (0.42) USP2PLA2G2CHSD17B10THRBKDM4E
Methacrylic Acid SCHEMBL11210689 0.78 USP2 (0.53) USP2PLA2G2CHSD17B10THRBKDM4E
SCHEMBL993470 0.75 ALDH1A1 (0.44) THRBTSHRTDP1
SCHEMBL9614400 0.75 USP2 (0.40) USP2PLA2G2CTHRBKDM4EDUSP3
SCHEMBL14673855 0.75 USP2 (0.41) USP2PLA2G2CHSD17B10THRBKDM4E
SCHEMBL5907719 0.73 THRB (0.58) USP2PLA2G2CHSD17B10THRBKDM4E
SCHEMBL1398234 0.73 TSHR (0.41) THRBKDM4EDUSP3MEN1KMT2A
SCHEMBL5838352 0.73 TSHR (0.41) THRBKDM4EDUSP3MEN1KMT2A
SCHEMBL1398249 0.73 TSHR (0.41) THRBKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200345542-A1 OPHTHALMIC COMPOSITION AND DELIVERY DEVICE THEREOF Sydnexis, Inc. 2020-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200345542-A1 OPHTHALMIC COMPOSITION AND DELIVERY DEVICE THEREOF CHRM3, CHRM2, CHRM4 USP2 1779/4885PLA2G2C 354/4885HSD17B10 2202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.