SCHEMBL11209397

SCHEMBL11209397

CCCCCCc1nc(CC(=O)O)c(CC)o1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
SCD O00767 1/20 0.38
CDC25A P30304 6/20 0.38
CDC25B P30305 6/20 0.38
CDC25C P30307 5/20 0.38
PPARA Q07869 7/20 0.36
EPHX2 P34913 1/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 1/20 0.36
PPARG P37231 6/20 0.35
PPARD Q03181 6/20 0.35
HDAC11 Q96DB2 5/20 0.35
TSHR P16473 4/20 0.35
GPR84 Q9NQS5 4/20 0.35
TLR2 O60603 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
FABP4 P15090 2/20 0.35
PTPN1 P18031 2/20 0.35
SLC22A6 Q4U2R8 1/20 0.35
SLC22A8 Q8TCC7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7218646 0.83 KDM4E (0.47) ALDH1A1SCDCDC25ACDC25BCDC25C
SCHEMBL4328042 0.75 SCD (0.44) ALDH1A1SCDPPARAEPHX2HSD17B10
SCHEMBL532911 0.73 MEN1 (0.36) ALDH1A1PPARAHSD17B10HPGDTSHR
SCHEMBL22150534 0.73 GABRP (0.39) ALDH1A1HSD17B10HPGDTSHRTDP1
SCHEMBL5008313 0.68 MEN1 (0.37) ALDH1A1CDC25ACDC25BCDC25CHSD17B10
SCHEMBL5701035 0.66 HCAR2 (0.44) ALDH1A1SCDPPARAHSD17B10PPARG
SCHEMBL23578521 0.66 PPARG (0.35) ALDH1A1SCDCDC25ACDC25BCDC25C
SCHEMBL7953996 0.66 ALDH1A1 (0.44) ALDH1A1SCDPPARAHSD17B10HPGD
SCHEMBL11496253 0.65 KMT2A (0.41) ALDH1A1PPARAHSD17B10HPGDTSHR
SCHEMBL23578435 0.65 GABRP (0.35) ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0096890-A2 Oxazoleacetic acid derivatives, process for their production and compositions containing said derivatives Takeda Chemical Industries, Ltd. (JP) 1983-12-28 EP disclosed