Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 6/20 | 0.36 |
| ▸ | CDC25B | P30305 | 6/20 | 0.36 |
| ▸ | CDC25C | P30307 | 5/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209397 | 0.83 | ALDH1A1 (0.41) | ALDH1A1HPGDHSD17B10SCDCDC25A | |
| SCHEMBL4483617 | 0.79 | TLR8 (0.33) | KDM4EALDH1A1HSD17B10NPC1CYP1A2 | |
| SCHEMBL3949713 | 0.77 | MEN1 (0.36) | ALDH1A1HSD17B10PPARANPC1CYP1A2 | |
| SCHEMBL23578521 | 0.76 | PPARG (0.35) | ALDH1A1SCDCDC25ACDC25BCDC25C | |
| SCHEMBL2839466 | 0.72 | HCAR2 (0.41) | KDM4EALDH1A1NPC1CYP1A2RAB9A | |
| SCHEMBL22150534 | 0.71 | GABRP (0.39) | KDM4EALDH1A1HPGDHSD17B10RXRA | |
| SCHEMBL5008313 | 0.69 | MEN1 (0.37) | KDM4EALDH1A1HPGDHSD17B10CDC25A | |
| SCHEMBL3738502 | 0.68 | GAA (0.74) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL7555134 | 0.68 | GAA (0.59) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL23588115 | 0.67 | PPARG (0.36) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003246781-A | METHOD FOR MANUFACTURING OXAZOLE COMPOUND | TAMA KAGAKU KOGYO KK | 2003-09-02 | — | — | JP | disclosed |