Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RYR2 | Q92736 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15761043 | 0.79 | — | — | |
| SCHEMBL13864441 | 0.79 | ALDH1A1 (0.47) | RYR2ACHEALDH1A1HPGDMAPT | |
| SCHEMBL4857897 | 0.79 | RYR2 (0.48) | RYR2ACHEALDH1A1HPGDMAPT | |
| SCHEMBL2077182 | 0.76 | TSHR (0.38) | ACHEALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL121521 | 0.70 | — | — | |
| SCHEMBL255965 | 0.70 | — | — | |
| SCHEMBL29965099 | 0.70 | — | — | |
| SCHEMBL7332054 | 0.70 | — | — | |
| SCHEMBL30560010 | 0.70 | — | — | |
| SCHEMBL9112992 | 0.70 | HTT (0.37) | MAPTTDP1MEN1KMT2AHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3885337-B1 | FTO INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2025-01-15 | — | — | EP | claimed |
| EP-3885337-A1 | FTO INHIBITORS | National Institute Of Biological Sciences, Beijing (CN) | 2021-09-29 | — | — | EP | claimed |
| US-20210238127-A1 | FTO Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-08-05 | — | — | US | claimed |
| US-10988440-B2 | FTO inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2021-04-27 | — | — | US | claimed |
| US-20200148628-A1 | FTO Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2020-05-14 | — | — | US | claimed |
| US-20180118665-A1 | FTO Inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-05-03 | — | — | US | claimed |
| EP-3303283-A1 | FTO INHIBITORS | National Institute Of Biological Sciences, Beijing (CN) | 2018-04-11 | — | — | EP | claimed |
| WO-2016206573-A1 | FTO INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2016-12-29 | — | — | WO | claimed |
| EP-2662351-B1 | Alkylated heterocyclic reaction products useful as antioxidants | SI GROUP INC (US) | 2016-03-30 | — | — | EP | claimed |
| EP-2084142-B1 | ALKYLATED HETEROCYCLIC REACTION PRODUCTS USEFUL AS ANTIOXIDANTS | SI GROUP INC (US) | 2016-03-23 | — | — | EP | claimed |
| EP-2662351-A1 | Alkylated heterocyclic reaction products useful as antioxidants | Albemarle Corporation (US) | 2013-11-13 | — | — | EP | claimed |
| US-8410084-B2 | Alkylated heterocyclic reaction products useful as antioxidants | ALBEMARLE CORPORATION (US) | 2013-04-02 | — | — | US | claimed |
| WO-2000035916-A1 | HERBICIDAL 4-BENZOYLISOXAZOLES | AVENTIS CROPSCIENCE S.A. (FR) | 2000-06-22 | — | — | WO | claimed |
| US-6048984-A | HERBICIDES AND ANTIGROWTH AGENTS | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2000-04-11 | — | — | US | claimed |
| US-5977376-A | Herbicidal 2-benzoylcyclohexane-1,3-diones and related compounds | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-11-02 | — | — | US | claimed |
| EP-0918056-A1 | Herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1999-05-26 | — | — | EP | claimed |
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | claimed |
| WO-1999003845-A1 | 2-BENZOYLCYCLOHEXANE-1,3-DIONE DERIVATIVES AS HERBICIDES AND INTERMEDIATES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | claimed |
| EP-0858452-A1 | THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-08-19 | — | — | EP | claimed |
| WO-1998004536-A1 | THIAZOLE DERIVATIVE AS PROTEIN KINASE C INHIBITORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1998-02-05 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180118665-A1 | FTO Inhibitors | FTO, ALKBH3, ALKBH1 | RYR2 4177/4885ACHE 2898/4885ALDH1A1 274/4885 |
| US-20210238127-A1 | FTO Inhibitors | FTO, ALKBH3, ALKBH1 | RYR2 4177/4885ACHE 2898/4885ALDH1A1 274/4885 |
| US-20200148628-A1 | FTO Inhibitors | FTO, ALKBH3, ALKBH1 | RYR2 4177/4885ACHE 2898/4885ALDH1A1 274/4885 |
| US-10988440-B2 | FTO inhibitors | FTO, ALKBH3, ALKBH1 | RYR2 4177/4885ACHE 2898/4885ALDH1A1 274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.