Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | VNN1 | O95497 | 4/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.42 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294064 | 0.82 | ATM (0.53) | ATMTDP1L3MBTL1SRD5A2VNN1 | |
| SCHEMBL11213960 | 0.82 | ATM (0.41) | ATMTDP1L3MBTL1SRD5A2VNN1 | |
| SCHEMBL11213109 | 0.81 | L3MBTL1 (0.40) | ATMTDP1L3MBTL1SRD5A2VNN1 | |
| SCHEMBL11480384 | 0.78 | ATM (0.52) | ATMTDP1L3MBTL1SRD5A2VNN1 | |
| SCHEMBL3684740 | 0.76 | ATM (0.63) | ATMTDP1L3MBTL1SRD5A2VNN1 | |
| SCHEMBL11210271 | 0.76 | PPARA (0.44) | MAPTSMN1; SMN2ALDH1A1RECQLHPGD | |
| SCHEMBL11482204 | 0.75 | ATM (0.45) | ATMTDP1L3MBTL1SRD5A2VNN1 | |
| SCHEMBL548283 | 0.75 | L3MBTL1 (0.61) | ATMTDP1L3MBTL1SRD5A2VNN1 | |
| SCHEMBL11210711 | 0.74 | AKR1C3 (0.39) | ATMTDP1MAPTPTGS1SMN1; SMN2 | |
| SCHEMBL7488968 | 0.73 | ATM (0.59) | ATMTDP1L3MBTL1SRD5A2VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0025262-B1 | ALPHA-THIO-ALPHA-ARYL-SUBSTITUTED ALKANONITRILES, PROCESS FOR THEIR PREPARATION, PROCESS FOR PREPARING ALPHA-ARYL-SUBSTITUTED ALKANONITRILES AND THE CORRESPONDING CARBOXYLIC ACIDS THEREFROM AND PROCESS FOR PREPARING INTERMEDIATES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4340740-A | Alpha-thio-alpha-aryl-substituted alkanonitrile and process for preparing alpha-aryl-substituted alkanonitrile therefrom | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1982-07-20 | — | — | US | disclosed |
| EP-0025262-A2 | Alpha-thio-alpha-aryl-substituted alkanonitriles, process for their preparation, process for preparing alpha-aryl-substituted alkanonitriles and the corresponding carboxylic acids therefrom and process for preparing intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-03-18 | — | — | EP | disclosed |