Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207374 | 0.81 | TDP1 (0.43) | PPARAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL11214109 | 0.79 | KMT2A (0.42) | PPARAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL11209428 | 0.76 | ATM (0.47) | MAPTALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL11213960 | 0.74 | ATM (0.41) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11212437 | 0.72 | PPARA (0.43) | PPARAMAPTNPC1RAB9ATSHR | |
| SCHEMBL11357018 | 0.72 | MAPT (0.51) | PPARAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL6576658 | 0.70 | PPARA (0.67) | PPARAMAPTMEN1KMT2ANPC1 | |
| SCHEMBL28294064 | 0.70 | ATM (0.53) | MAPTALDH1A1HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL11213109 | 0.69 | L3MBTL1 (0.40) | ALDH1A1 | |
| SCHEMBL11288824 | 0.68 | POLB (0.51) | PPARAMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56138175-A | — | — | None | — | — | JP | disclosed |
| EP-0025262-B1 | ALPHA-THIO-ALPHA-ARYL-SUBSTITUTED ALKANONITRILES, PROCESS FOR THEIR PREPARATION, PROCESS FOR PREPARING ALPHA-ARYL-SUBSTITUTED ALKANONITRILES AND THE CORRESPONDING CARBOXYLIC ACIDS THEREFROM AND PROCESS FOR PREPARING INTERMEDIATES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1983-10-05 | — | — | EP | disclosed |
| US-4340740-A | Alpha-thio-alpha-aryl-substituted alkanonitrile and process for preparing alpha-aryl-substituted alkanonitrile therefrom | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1982-07-20 | — | — | US | disclosed |
| JP-S56138175-A | ALPHA- 2-BENZOTHIAZOLYLTHIO -ALPHA-ARYL GROUP SUBSTITUTED ALKANONITRILE | SAGAMI CHEM RES CENTER | 1981-10-28 | — | — | JP | disclosed |
| EP-0025262-A2 | Alpha-thio-alpha-aryl-substituted alkanonitriles, process for their preparation, process for preparing alpha-aryl-substituted alkanonitriles and the corresponding carboxylic acids therefrom and process for preparing intermediates | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-03-18 | — | — | EP | disclosed |