Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2069938 | 0.81 | CYP19A1 (0.60) | NPC1POLBRAB9APKMHTT | |
| SCHEMBL2070549 | 0.79 | MAPT (0.70) | NPC1POLBRAB9APKMHTT | |
| SCHEMBL2070257 | 0.78 | PKM (0.78) | PKMHTTMAPTALDH1A1KMT2A | |
| SCHEMBL2070357 | 0.78 | KMT2A (0.55) | RAB9APKMHTTMAPTALDH1A1 | |
| SCHEMBL11159531 | 0.78 | MAPT (0.62) | NPC1RAB9APKMHTTMAPT | |
| SCHEMBL10814140 | 0.78 | ALDH1A1 (0.52) | POLBMAPTALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2073096 | 0.77 | ALDH1A1 (0.54) | NPC1POLBRAB9APKMHTT | |
| SCHEMBL2069778 | 0.77 | MAPT (0.69) | NPC1POLBRAB9APKMHTT | |
| SCHEMBL7576322 | 0.77 | ALDH1A1 (0.56) | PKMHTTMAPTALDH1A1KMT2A | |
| SCHEMBL11086324 | 0.76 | KMT2A (0.76) | NPC1POLBHTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027940-B1 | PROCESS FOR PREPARING URETHANES | BAYER AG (DE) | 1983-09-14 | — | — | EP | disclosed |