Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2070712 | 0.90 | SMN1; SMN2 (0.55) | ALDH1A1KMT2AMAPTSMN1; SMN2CYP2C9 | |
| SCHEMBL2070549 | 0.86 | MAPT (0.70) | ALDH1A1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL11159531 | 0.85 | MAPT (0.62) | ALDH1A1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL2070357 | 0.85 | KMT2A (0.55) | ALDH1A1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL2069778 | 0.84 | MAPT (0.69) | ALDH1A1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL7576322 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL11086324 | 0.83 | KMT2A (0.76) | ALDH1A1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL2070257 | 0.83 | PKM (0.78) | ALDH1A1KMT2AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL3010106 | 0.81 | HTT (0.52) | ALDH1A1KMT2AMAPTSMN1; SMN2PKM | |
| SCHEMBL9119558 | 0.81 | POLB (0.66) | ALDH1A1KMT2AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906537-B2 | Substituted p-diaminobenzene derivatives | H. LUNDBECK A/S (DK) | 2011-03-15 | — | — | US | disclosed |
| US-20060183791-A1 | Substituted p-diaminobenzene derivatives | H. LUNDBECK A/S (DK) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183791-A1 | Substituted p-diaminobenzene derivatives | ABCB1, UGT2B7, CYP2D6 | ALDH1A1 112/4885KMT2A 3706/4885MAPT 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.