Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424728 | 0.83 | TSHR (0.73) | TSHRLMNATYRKIF11ALDH1A1 | |
| SCHEMBL545084 | 0.83 | TSHR (0.67) | TSHRLMNAMAPK1TDP1 | |
| SCHEMBL9816151 | 0.83 | TSHR (0.67) | TSHRLMNAMAPK1TDP1 | |
| SCHEMBL13704994 | 0.81 | TSHR (0.55) | TSHRLMNATYRKIF11ALDH1A1 | |
| SCHEMBL11551232 | 0.81 | TSHR (0.52) | TSHRLMNATYRALDH1A1HPGD | |
| SCHEMBL7565907 | 0.81 | TSHR (0.55) | TSHRLMNATYRKIF11ALDH1A1 | |
| SCHEMBL18242376 | 0.77 | TSHR (0.46) | TSHRLMNATYRALDH1A1HSD11B1 | |
| Hydrogen Peroxide SCHEMBL28677809 | 0.76 | LMNA (0.71) | TSHRLMNATYRKIF11ALDH1A1 | |
| SCHEMBL1538589 | 0.75 | TSHR (0.55) | TSHRLMNAALDH1A1HPGDNPC1 | |
| SCHEMBL8889645 | 0.75 | TSHR (0.55) | TSHRLMNATYRKIF11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045425-B1 | PROCESS FOR THE HALOGENATION OF POSSIBLY SUBSTITUTED 4-TERT.-BUTYL TOLUENES AND THE MIXTURES OBTAINED THEREFROM OF POSSIBLY SUBSTITUTED 4-TERT.-BUTYLBENZAL HALOGENIDES, 4-TERT.-BUTYLBENZYL HALOGENIDES AND 4-TERT.-BUTYLBENZO TRIHALOGENIDES | BAYER AG (DE) | 1983-11-23 | — | — | EP | disclosed |
| US-4306102-A | CHEMICAL INTERMEDIATES IN THE FORMATION OF P-TERT-BUTYL BENZOIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-12-15 | — | — | US | disclosed |
| EP-0011288-A1 | p-Tert.-butylbenzotribromide and his derivatives which are substituted in the ring by halogen, a process for their preparation as well as their use. | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-28 | — | — | EP | disclosed |
| US-4163753-A | FROM AN ALIPHATIC ACID ANHYDRIDE AND A TRICHLOROMETHYL AROMATIC COMPOUND | Diaz Chemical Corporation (US) | 1979-08-07 | — | — | US | disclosed |