Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14480099 | 1.00 | LMNA (0.61) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL11209565 | 1.00 | LMNA (0.61) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL27622870 | 0.79 | L3MBTL1 (0.63) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL213141 | 0.79 | LMNA (0.63) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL5732924 | 0.79 | LMNA (0.63) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL2615557 | 0.79 | LMNA (0.63) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL27927629 | 0.77 | LMNA (0.61) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL20997773 | 0.76 | LMNA (0.59) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL23635710 | 0.74 | LMNA (0.74) | LMNAL3MBTL1MAPK1HTTMAPT | |
| SCHEMBL14667470 | 0.74 | MAPT (0.60) | LMNAL3MBTL1MAPK1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030702-B1 | PROPIONIC-ACID ESTERS, PREPARATION OF THESE COMPOUNDS, HERBICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, USE OF SUCH COMPOUNDS AND AGENTS AS HERBICIDES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-08-24 | — | — | EP | claimed |